The National Hellenic Research Foundation, one of the largest Research Centers in Greece, was founded in 1958 originally under the name "Royal Research Foundation". It is a non-profit Research Foundation supervised by the General Secretariat for Research and Technology (GSRT) of the Ministry of Development and Investments in Greece.

Today, NHRF consists of the following Institutes and Units:

Institute of Historical Research (IHR/NHRF)

The Institute emerged in 2012 following the fusion of the Institute of Greek & Roman Antiquity, the Institute of Byzantine Research and the Institute of Neohellenic Research (L.4051/29/2/2012, article 5, par.2). The IHR conducts research on the history and culture of the Greek areas and the regions where Hellenism has been active, from prehistoric antiquity to the modern era.

Institute of Chemical Biology (ICB/NHRF)

ICB (former IBMCB) was established in 2012 as a result of the consolidation of the Institute of Biological Research and Biotechnology and the Institute of Organic and Pharmaceutical Chemistry of NHRF (L.4051/29/2/2012, article 5, par.2). ICB acts as a focal point, unique within Greece, for innovation at the interface of Chemistry and Biology through a modern interdisciplinary approach to the solution of state-of-the-art issues in the areas of health, drug discovery, biomarker research and biotechnology.

Institute of Theoretical and Physical Chemistry (TPCI/NHRF)

TPCI was established in 1979 from the merging of the Institutes of Physical Chemistry (est.1968) and Theoretical Chemistry (est.1976). TPCI advances research in selected fields of experimental and computational/theoretical chemistry and physics, with emphasis on nanomaterials with advanced functionality for energy conversion and storage, photonics, and electrochemical applications.


NHRF Research Highlights





Due to the emergency of the CoViD-19 that has developed in the past weeks in Greece and worldwide, the Institute of Historical Research of the National Hellenic Research Foundation has decided to cancel the Summer School in Byzantine Script and Book Culture (22-27/6/2020) and the Summer School on Ancient Greek and Roman Numismatics (1-10/7/2020) that were to take place in the summer of 2020.
The acceleration of the epidemic, the increasingly restrictive measures announced by the authorities and the overall disruption to travel and economy obliged us to take this decision to protect the health of the participants and the population at large.
Both summer schools are being rescheduled for the summer 2021.



The National Hellenic Research Foundation currently participates in the research project NEOVIOPRO for the identification of biomarkers in prostate cancer. The identification of prognostic biomarkers of the clinical course of the disease, as well as of predictive biomarkers of the response to a therapeutic approach, constitutes the subject of investigation and aims at a timely and more effective treatment of the disease.


RIS3 "AGROFOOD" Unlike other vegetable oils, olive oil has a high content of high-quality fatty acids suitable for the infant. This makes it ideal for use as a raw material in infant formula. ELAION project aims for the first time, to utilize olive oil in infant formulas in a pilot scale infant formula production unit in the Region of Western Greece.


Bioinspired antiageing proteasome activators

RESET relies on the active collaboration between InterMed SA, and the Institute of Chemical Biology/NHRF

Research results for the Kasos Maritime Archaeological Project.


CO2 BioProducts project aims at the systematic exploitation of the microalgal ability to produce a broad range of biochemical and bioactive high added-value ingredients which can be used by various industries, e.g. cosmetics and dietary products.

Pfizer and National Hellenic Research Foundation (NHRF): Powerful Alliance towards “Advancing Science”


New research paper by the group of Dr. Georgios Skretas in Science Advances describes the development of engineered bacteria with the ability to produce hundreds of millions of molecules and perform rapid and efficient discovery of new drugs

HealthSpan logo

«RESEARCH-CREATE-INNOVATE» Health Span project, is based on the collaboration of Qualia Pharma S.A. with the National Hellenic Research Foundation (NHRF). The project aims to the development of a new dietary supplement, that will promote well-being and longevity.

Presentation of The good story of dogs who helped pharmacologists in the discovery of a new drug against Leishmaniasis.
The New Medicines for Trypanosomatidic Infections (NMTrypI) 2014-2017. GA603240. FP7 European project presents the video about the dog trial performed during the project implementation: (dog trial of NMT-A2) and its 2 years follow-up after the project end (2018-2019).

The National Hellenic Research Foundation coordinates the QFytoTera research consortium in the effort to develop innovative repellent products that prevent spread of insect-borne diseases

Press Release
Dr. Georgios Skretas, Senior Researcher at the National Hellenic Research Foundation, is awarded a Consolidator Grant from the European Research Council (ERC) to develop engineered bacteria that accelerate drug discovery against diseases caused by protein misfolding.

Press Release
14 Early Stage Researchers (Marie-Curie Fellows) to be trained in a European training network for the discovery of small molecule neurotrophin mimetics as candidate therapeutic agents for neurodegeneration and neuro-inflammation.

A new weapon in the battle against cancer; Athens based Comprehensive Cancer Research Center

Engineered bugs for the discovery of new drugs

The National Hellenic Research Foundation represents the Hellenic Republic in the European Research Infrastructure Consortium «Integrated Structural Biology», Instruct-ERIC as an Observer

Chemical tuning MoS2 for energy applications: Living on the edge
A new interdisciplinary study from groups at the Theoretical and Physical Chemistry Institute (TPCI) of the National Hellenic Research Foundation (NHRF), Athens, the Institut des Materiaux Jean Rouxel – CNRS Nantes, France, the Instituto de Nanociencia, Universidad de Zaragoza, Spain, all within the H2020 Marie Curie ITN “Enabling Excellence” project, and Chimie des Interactions Plasma-Surface, University of Mons, Belgium, proves that 1,2-dithiolane derivatives can covalently anchored preferentially at the MoS2 sheet edges. This key result presents an important piece to the puzzle of 2D materials’ chemistry.

Unraveling the drug-resistance mechanisms in tumor cells

Contactless manipulation of nano-matter

Making use of recent advances in nanotechnology, novel optical nano-tweezers were developed by researchers of the Theoretical and Physical Chemistry Institute at the National Hellenic Research Foundation (NHRF) in Athens, Greece, in collaboration with researchers of the Department of Physics and Astronomy at the University of Southampton, UK.

Τhe Essential Role of s36 Protein in the Architectural Organization of Drosophila melanogaster Chorion

Interdisciplinary studies from groups at the Theoretical and Physical Chemistry Institute (TPCI) in National Hellenic Research Foundation (NHRF), the Section of Cell Biology and Biophysics in Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), the Proteomics Core Facility, Systems Biology Center in Biomedical Research Foundation of the Academy of Athens (BRFAA), and the Laboratory of Experimental Physiology in Medical School, National and Kapodistrian University of Athens (NKUA), unveil the essential contribution of s36 protein in the assembly and architecture of Drosophila chorion and the novel function of s36 chorionic protein in the regulation of number and morphogenetic integrity of dorsal appendages in follicles sporadically undergoing aged fly-dependent stress.

Ice-covered C60 crystals, an interstellar birthplace for early life?

A new interdisciplinary study from groups at the Theoretical and Physical Chemistry Institute (TPCI) in National Hellenic Research Foundation (NHRF), Athens, Greece, the Institute of Materials Jean Rouxel in Nantes, and other laboratories across Europe and Canada

Study performed by IBMCB/NHRF groups is awarded in the 1st International Conference on Pharmaceutical Bioinformatics

Underwater archaeological research at the northeast area of Delos (2014-15), a collaboration of the Institute of Historical Research (IHR) of the National Hellenic Research Foundation (NHRF) with the Ephorate of Underwater Antiquities.

Creation of an NHRF spin-off bionformatics company with funding from the PJ Tech Catalyst Fund and IQbility

The new electronic platform for the journal of the Section of Greek and Roman Antiquity (SGRA) Tekmeria ( index.php/tekmiria) and the new issue 11 (2012) of our journal are now available online.


May 2020

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Presentation of the National Hellenic Research Foundation (NHRF) by the Director and President of the Board, Dr. Vasilis Gregoriou

Presentation of the Institute of Historial Research (IHR) by Deputy Director Dr. Harikleia Papageorgiadou and Research Director, Dr. Kountoura-Galake Eleonora

Presentation of the Institute of Biology, Medicinal Chemistry and Biotechnology (IBMCB) by the Director Dr. Alexandros Pintzas, with the participation of Post-Doctoral Researcher, Dr. Eftychia Kritsi

Presentation of the Theoretical and Physical Chemistry Institute (TPCI) by the Director Dr. Efstratios I. Kamitsos and Associate Researcher, Dr. Christos Riziotis


Institute of Historical Research Bookstore