Materials Synthesis and Physical Chemistry
  Carbon nanostructures and two-dimensional nanomaterials
  Block copolymer synthesis and self-assembled nanostructures
  Nanostructured biomaterials
  Énvestigations using vibrational spectroscopy/microscopy (Raman and infrared)
AFM/Raman correlative microscopy

  Clay minerals and clay-based hybrid materials
  Low dimensional Hybrid Materials
  Synthesis and physicochemical properties of advanced organic-inorganic materials
  Design and development of Metal Organic Frameworks and/or Covalent Organic Frameworks
  Design and construction of artificial photosynthetic systems for the conversion of solar energy to fuels

Material Synthesis and Physical Chemistry

Design and development of Metal Organic Frameworks and/or Covalent Organic Frameworks
Dr. Giasemi Angeli, Associate Researcher
orcid googleholar

Dr Giasemi Angeli is leading the "Design and development of Metal Organic Frameworks and/or Covalent Organic Frameworks" activity within the Materials Synthesis and Physical Chemistry direction of the Theoretical and Physical Chemistry Institute. Our research concerns the design and synthesis of novel and appropriately functionalized porous frameworks targeting cutting edge applications. Our objective is through Reticular Chemistry implementation to synthesize functional porous materials with tailored physicochemical characteristics aiming to contribute to the transition from traditional fossil fuels to more environmentally friendly sources as well as to the quality improvement of urban air and water. Our work includes the design and synthesis of functionalized linkers as well as the synthesis of porous frameworks as well as appropriately designed porous composite materials using solvothermal synthetic procedures assisted by a wide range of post synthetic modification approaches. Furthermore, our research interests include the detailed characterization of the synthesized materials regarding their structural and physicochemical characteristics using state-of-the art methods, as crystallography, porosimetry and electron Microscopy.


Research Highlights


J. Am. Chem. Soc. 2021, 143, 10250


J. Am. Chem. Soc. 2020, 142, 15986


ACS Appl. Mater. Interfaces 2017, 51, 44560


Current Members

Dr. Giasemi Angeli, Associate Researcher





Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation
Dr Emmanuel Klontzas, Associate Researcher



Prof. Pantelis N. Trikalitis,
Department of Chemistry, University of Crete

Prof Konstantinos Demadis,
Department of Chemistry, University of Crete

Prof Constantinos Neochoritis,
Department of Chemistry, University of Crete

Dr Constantinos Tsangarakis,
Department of Chemistry, University of Crete

Dr Theodore Steriotis,
National Centre for Scientific Research "Demokritos"

Dr Georgia Charalampopoulou,
National Centre for Scientific Research "Demokritos"



Prof Ioannis Spanopoulos,
Department of Chemistry, University of South Florida, USA

Prof. Dina Maniar,
Zernike Institute for Advanced Materials, Groningen, The Netherlands

Dr Eleni Thomou,
Zernike Institute for Advanced Materials, Groningen, The Netherlands

Dr Edward Loukopoulos,
Universidad Autonoma de Madrid, Spain





  • Accessing 14-Connected Nets: Continuous Breathing, Hydrophobic Rare-Earth Metal Organic Frameworks Based on 14-c Hexanuclear Clusters with High Affinity for Non-Polar Vapors Edward Loukopoulos, Giasemi K. Angeli, Konstantinos Kouvidis, Constantinos Tsangarakis, and Pantelis N. Trikalitis, ACS Appl. Mater. Interfaces 2022, 14, 22242.
    DOI: 10.1021/acsami.2c05961
  • Local Anesthetics via Multicomponent Reactions M. Thomaidi, L.-E. Vagiaki, N. P. Tripolitsiotis, G. K. Angeli, T. Zarganes-Tzitzikas, K. Sidiropoulou, C. G. Neochoritis, ChemMedChem 2022, 17, e202200246.
    DOI: 10.1002/cmdc.202200246
  • Sustainable multicomponent indole synthesis with broad scope, Xiaofang Lei, Giasemi K. Angeli, Constantinos G. Neochoritis and Alexander Domling, Green Chem 2022, 24, 6168.
    DOI: 10.1039/D2GC02060B
  • Dibenzothiazepine Based MCR Chemistry, Xiaofang Lei, Dr. Giasemi Angeli, Prof. Alexander Domling, Prof. Constantinos G. Neochoritis, Eur. J. Org. Chem. 2022, 20, e202200220.
    DOI: 10.1002/ejoc.202200220


  • Continuous Breathing Rare-Earth MOFs Based on Hexanuclear Clusters with Gas Trapping Properties, Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, and Pantelis N. Trikalitis, J. Am. Chem. Soc. 2021 143, 10250.
    DOI: 10.1021/jacs.1c03762
  • A multicomponent tetrazolo indole synthesis, Xiaofang Lei, Panagiota Lampiri, Pravin Patil, Giasemi Angeli, Constantinos G. Neochoritis, Alexander Domling, Chem. Commun. 2021, 57, 6652.
    DOI: 10.1039/D1CC02384E 
  • Fluorene-Based Multicomponent Reactions, Xiaofang Lei, Maria Thomaidi, Giasemi K. Angeli, Alexander Domling, Constantinos G. Neochoritis Synlett 2021, st-2021-b0083-l.
    DOI: 10.1055/a-1471-9080
  • A diamino-functionalized silsesquioxane pillared graphene oxide for CO2 capture, Eleni Thomou, Viktoria Sakavitsi, Giasemi K.Angeli, Konstantinos Spyrou, Konstantinos Froudas, Evmorfia K. Diamanti, George E. Romanos, Georgios N. Karanikolos, Pantelis N. Trikalitis, Dimitrios Gournis and Petra Rudolf RSC Advances 2021, 11(23), pp. 13743.
    DOI: 10.1039/D1RA00777G


  • Remarkable Structural Diversity between Zr/Hf and Rare-Earth MOFs via Ligand Functionalization and the Discovery of Unique (4, 8)-c and (4, 12)-connected Framework, Giasemi K. Angeli, Danai Batzavali, Katerina Mavronasou, Constantinos Tsangarakis, Tobias Stuerzer, Holger Ott, and Pantelis N. Trikalitis J. Am. Chem. Soc. 2020 142, 15986.
    DOI: 10.1021/jacs.0c07081
  • Improving the Cd2+ detection capability of a new anionic rare earth metal-organic framework based on a [RE63-OH)8]10+ secondary building unit: an ion-exchange approach towards more efficient sensors, Nikos Panagiotou, Kasiani Evangelou, Athanasia Psalti, Nektaria Varnava, Giasemi K. Angeli, Pantelis N. Trikalitis, John C. Plakatouras, Theodore Lazarides and Anastasios J. Tasio-poulos Mol. Syst. Des. 2020 Eng.,5, 1077.
    DOI: 10.1039/C9ME00176J
  • Water-stable 2-D Zr MOFs with exceptional UO22+ sorption capability, Nikos Panagiotou, Ioanna Liatsou,a Anastasia Pournara, Giasemi K. Angeli, Rafaela Maria Giappa, Emmanuel Tylianakis, Manolis J. Manos, George E. Froudakis, Pantelis N. Trikalitis, Ioannis Pashalidis and Anastasios J. Tasiopoulos. J. Mater. Chem. A 2020, 8, 1849.
    DOI: 10.1039/C9TA10701K


  • Water Interaction with Mineral Dust Aerosol: Particle Size and Hygroscopic Properties of Dust, Ibrahim, S., Romanias, M.N., Alleman, L.Y., Zeineddine, M.N., Angeli, G.K., Trikalitis, P.N., Thevenet, F., ACS Earth and Space Chemistry 2018 4, 376
    DOI: 10.1021/acsearthspacechem.7b00152




  • Structural Stability, Vibrational Properties, and Photoluminescence in CsSnI3 Perovskite upon the Addition of SnF2, Athanassios G. Kontos, Andreas Kaltzoglou, Eirini Siranidi, Dimitrios Palles, Giasemi K. Angeli, Michalis K. Arfanis, Vassilis Psycharis, Yannis S. Raptis, Efstratios I. Kamitsos, Pantelis N. Trikalitis, Constantinos C. Stoumpos, Mercouri G. Kanatzidis, Polycarpos Falaras, Inorg Chem 2017, 56, 84.
    DOI: 10.1021/acs.inorgchem.6b02318 
  • Reticular Chemistry and the Discovery of a New Family of Rare Earth (4, 8)-Connected Metal-Organic Frameworks with csq Topology Based on RE43-O)2(COO)8 Clusters, Giasemi K. Angeli, Christina Sartsidou, Styliani Vlachaki, Ioannis Spanopoulos, Constantinos Tsangarakis, Andreas Kourtellaris, Emmanuel Klontzas, George E. Froudakis, Anastasios Tasiopoulos, and Pantelis N. Trikalitis ACS Appl. Mater. Interfaces 2017, 51, 44560. 
    DOI: 10.1021/acsami.7b16380 



  • Luminescent and Proton Conducting Lanthanide Hybrid Materials Based on a Zwitterionic Tripodal Triphosphonate, Bazaga-Garcia, Montse; Angeli, Giasemi; Papathanasiou, Konstantinos; Salcedo, Ines; Olivera-Pastor, Pascual; Losilla, Enrique; Choquesillo-Lazarte, Duane; Hix, Gary; Cabeza, Aurelio; Demadis, Konstantinos, Inorg Chem 2016, 55, 7414. 
    DOI: 10.1021/acs.inorgchem.6b00570 



  • Structural Variability in Multifunctional Metal Xylenediaminetetraphosphonate Hybrids, Colodrero, Rosario; Angeli, Giasemi; Bazaga-Garcia, Montse; Olivera-Pastor, Pascual; Villemin, Didier; Losilla, Enrique; Martos, Estefania; Hix, Gary; Aranda, Miguel; Demadis, Konstantinos; Cabeza, Aurelio, Inorg Chem 2013; 52, 8770.
    DOI: 10.1021/ic400951s 
  • “Good scale”-“bad scale”: How metal-phosphonate materials contribute to corrosion inhibition, Giasemi Angeli, Konstantinos D. Demadis Mineral Scales in Biological and Industrial Systems 2013, 353.
    DOI: 10.1201/b15606








© National Hellenic Research Foundation (NHRF), 48 Vassileos Constantinou Ave., 11635 Athens, Greece, Tel. +302107273700, Fax. +302107246618