TPCI - Materials Syntesis and Physical Chemistry

Greek

THEORETICAL & PHYSICAL CHEMISTRY INSTITUTE


	Photonics for Nano-applications
	Laser structuring and functionalization of materials and devices :: Laser micro/nanostructuring for smart surfaces, photonic and optoelectronic applications :: Development and applications of nanocomposite thin films
	The Short Light Wavelengths and Applications Laboratory :: Stimulus-perception laws of cells :: Complexity, hierarchy and biophysics of cancer cells :: Microwave spectroscopy, technology, and applications
	Optical Fiber Devices and Sensors :: Fabrication and hybridization of optical microfibers :: Hybrid Photonic Crystal Fibers (HPCFs)
	Applied Photonics-Materials & Devices - APMD :: Development of Low Cost and Autonomous Photonic Sensors :: Engineering of Plasmonic and Non-Linear Photonic Devices :: Planar Optical Components & Multifunctional Integrated Optical Circuits :: Photonic Engineering for Biomedical and Sensing Applications

Photonics for Nano-applications

Stimulus-perception laws of cells

Dr. E. Sarantopoulou, Senior Researcher

Dr. Z. Kollia, Scientific/Technical Staff

Nanoscale stimulus-perception reaction of cells elucidates bio-memory at different hierarchies and adaption and viability at extreme environmental conditions.
The unusual high cell viability at extreme environmental conditions is deciphered by applying novel mathematical models of complexity and hierarchy and also experimental approaches (Nano-indentation, Raman spectroscopies, DNA electrophoresis). Cell’s viscoelastic and noise signatures are exposed by measuring and evaluating the scaling exponents of relaxation functions and the power spectral densities. The novel methodologies exploit nano-resolution of force-time derivatives and demonstrate bio-memory in cells under harmful external stressing. The results elucidate the notable high viability of fungal cells under harsh Space conditions, including exposure to Solar radiation (VUV), low and high vacuum and temperature, and the high resistivity of cancer cells to chemotherapy.

Key publications

J. Phys. Chem. B 2021, 125, 10883

J. Appl. Phys. 2014, 116, 104701

Recent publications (since 2013)

Stimulus-perception laws of cells

Viscoelasticity and noise properties reveal the formation of biomemory in cells, J. Phys. Chem B 2021, 125, 10883
DOI: 10.1021/acs.jpcb.1c01752
Viability of Cladosporium herbarum spores under 157 nm laser and vacuum ultraviolet irradiation, low temperature (10 K) and vacuum, J. Appl. Phys. 2014, 116, 104701
DOI: 10.1063/1.4894621