THEORETICAL & PHYSICAL CHEMISTRY INSTITUTE
 
  Photonics for Nano-applications
  Laser structuring and functionalization of materials and devices
  The Short Light Wavelengths and Applications Laboratory
  Optical Fiber Devices and Sensors
  Applied Photonics-Materials & Devices - APMD

Photonics for Nano-applications

Stimulus-perception laws of cells
Dr. E. Sarantopoulou, Senior Researcher
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Dr. Z. Kollia, Scientific/Technical Staff
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Nanoscale stimulus-perception reaction of cells elucidates bio-memory at different hierarchies and adaption and viability at extreme environmental conditions.
The unusual high cell viability at extreme environmental conditions is deciphered by applying novel mathematical models of complexity and hierarchy and also experimental approaches (Nano-indentation, Raman spectroscopies, DNA electrophoresis). Cell’s viscoelastic and noise signatures are exposed by measuring and evaluating the scaling exponents of relaxation functions and the power spectral densities. The novel methodologies exploit nano-resolution of force-time derivatives and demonstrate bio-memory in cells under harmful external stressing. The results elucidate the notable high viability of fungal cells under harsh Space conditions, including exposure to Solar radiation (VUV), low and high vacuum and temperature, and the high resistivity of cancer cells to chemotherapy.

 

Key publications

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J. Phys. Chem. B  2021, 125, 10883

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J. Appl. Phys. 2014, 116, 104701

   

 

Recent publications (since 2013)

Stimulus-perception laws of cells
  • Viscoelasticity and noise properties reveal the formation of biomemory in cells, J. Phys. Chem B 2021, 125, 10883
    DOI: 10.1021/acs.jpcb.1c01752
  • Viability of Cladosporium herbarum spores under 157 nm laser and vacuum ultraviolet irradiation, low temperature (10 K) and vacuum, J. Appl. Phys. 2014, 116, 104701
    DOI: 10.1063/1.4894621

 

 

 

 

 

 

 

 

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